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Agrochem。研究团队筛选出根结线虫属中1个高度保守且安全的靶标基因,配套研发双链RNA稳定递送体系,沉默该基因可精准阻断线虫的应激免疫通路,干扰线虫正常发育进程。田间根结线虫综合防控效果达78.4%,实现了从靶点挖掘、机理阐释到田间验证的全程技术闭环,为土传线虫绿色防控产品开发奠定技术基础。","根结线虫是严重危害粮食和经济作物的重要土传有害生物。RNA干扰技术靶向精准、环境友好，但核酸易降解、摄取效率低，长期制约田间应用。\n\n研究团队筛选出根结线虫属中1个高度保守且安全的靶标基因，配套研发出双链RNA稳定递送体系。研究表明，沉默该基因可精准阻断线虫的应激免疫通路，干扰线虫正常发育进程。\n\n该技术大幅提升靶标基因沉默效果，线虫幼虫致死率显著提高，田间根结线虫的综合防控效果达78.4%，实现了从靶点挖掘、机理阐释到田间验证的全程技术闭环，为土传线虫绿色防控产品开发奠定了坚实的技术基础。","中国农业科学院 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根结线虫","中国农科院根结线虫绿色防控植保所-394",4,"2026-08-11T23:57:01.465653Z",{"id":226,"title":227,"url":228,"summary":229,"summary_zh":8,"content":189,"source_name":230,"source_url":8,"published_at":231,"category":11,"cover_url":8,"hotness":12,"is_selected":13,"score":232,"score_detail":233,"sources":235,"tags":237,"primary_topic":239,"secondary_topics":240,"classification":241,"search_phrases":252,"slug":253,"view_count":254,"doi":8,"paper":8,"created_at":255},253,"RNA干扰技术让根结线虫防控效果达78%——中国农科院植保所联合多家单位研发土传线虫绿色防控新技术","https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fmtxw\u002F08228a253deb412299a58cc31647ed8e.htm","近日,中国农业科学院植物保护研究所联合多家科研单位,成功研发出以RNA干扰为核心的根结线虫绿色防控技术,相关研究成果发表在《现代农业化学》(Advanced Agrochem)上。根结线虫是严重危害粮食和经济作物的重要土传有害生物,RNA干扰技术靶向精准、环境友好,但核酸易降解、摄取效率低,长期制约田间应用。研究团队筛选出根结线虫属中1个高度保守且安全的靶标基因,配套研发出双链RNA稳定递送体系。研究表明,沉默该基因可精准阻断线虫的应激免疫通路,干扰线虫正常发育进程,大幅提升靶标基因沉默效果,线虫幼虫致死率显著提高,田间根结线虫的综合防控效果达78.4%,实现从靶点挖掘、机理阐释到田间验证的全程技术闭环,为土传线虫绿色防控产品开发奠定坚实技术基础。","中国科学报 2026-08-06","2026-08-06T00:00:00Z",80,{"impact":194,"substance":195,"depth":196,"authority":91,"freshness":56,"relevant":21,"comment":234},"农业科技重大突破，RNA干扰技术防控根结线虫效果显著，具有产业应用前景。",[236],{"name":230,"url":228},[202,27,28,29,203,238],"Advanced Agrochem",{"code":39,"slug":40,"name":41,"path":42,"parent_code":43},[],{"status":45,"locked":13,"version":46,"method":47,"evidence":242},{"candidates":243,"agricultural_evidence":51},[244,248],{"code":39,"score":210,"supported":51,"title":245,"abstract":246,"tags":247},[212,29],[29],[27,29],{"code":68,"score":21,"supported":13,"title":249,"abstract":250,"tags":251},[],[],[29],[220,221],"中国农科院根结线虫绿色防控植保所-253",7,"2026-08-07T00:18:29.965382Z",{"id":257,"title":258,"url":259,"summary":260,"summary_zh":8,"content":8,"source_name":261,"source_url":8,"published_at":262,"category":263,"cover_url":8,"hotness":12,"is_selected":13,"score":264,"score_detail":265,"sources":268,"tags":270,"primary_topic":271,"secondary_topics":272,"classification":273,"search_phrases":284,"slug":286,"view_count":56,"doi":8,"paper":8,"created_at":287},116,"RNA干扰技术开辟根结线虫防控新路径","https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyjz\u002F202607\u002Ft20260717_6000492.htm","中国农业科学院植物保护研究所联合多家科研单位,成功研发出以RNA干扰为核心的根结线虫绿色防控技术,相关研究成果发表在国际期刊。该技术为根结线虫防控开辟了新路径,具有重要的农业应用价值。","中国农业科学院 2026-07-17","2026-07-17T01:00:00Z","论文",81,{"impact":266,"substance":194,"depth":18,"authority":134,"freshness":21,"relevant":21,"comment":267},25,"国家级科研机构重大突破，论文成果具有产业级影响，但时效性较差。",[269],{"name":261,"url":259},[202,27,28,29],{"code":39,"slug":40,"name":41,"path":42,"parent_code":43},[],{"status":45,"locked":13,"version":46,"method":47,"evidence":274},{"candidates":275,"agricultural_evidence":51},[276,280],{"code":39,"score":197,"supported":51,"title":277,"abstract":278,"tags":279},[],[29],[27,29],{"code":68,"score":21,"supported":13,"title":281,"abstract":282,"tags":283},[],[],[29],[285,221],"中国农科院 根结线虫 绿色防控 RNA干扰","中国农科院根结线虫绿色防控RNA干扰-116","2026-07-31T00:00:56.128565Z",{"id":289,"title":290,"url":291,"summary":292,"summary_zh":293,"content":8,"source_name":294,"source_url":291,"published_at":295,"category":263,"cover_url":8,"hotness":12,"is_selected":13,"score":296,"score_detail":297,"sources":299,"tags":301,"primary_topic":305,"secondary_topics":306,"classification":313,"search_phrases":354,"slug":357,"view_count":358,"doi":359,"paper":360,"created_at":373},5158,"POTATO LATE BLIGHT CAUSED BY PHYTOPHTHORA INFESTANS: BIOLOGY,EPIDEMIOLOGY, CLIMATE CHANGE, AND SUSTAINABLE MANAGEMENT STRATEGIES","https:\u002F\u002Fdoi.org\u002F10.56093\u002Fpotatoj.v53i1.181670","Potato late blight, caused by Phytophthora infestans, remains one of the mostdestructive diseases affecting global potato production, resulting in substantial yield and economiclosses. This review summarizes the pathogen’s biology, disease cycle, epidemiology, host–pathogeninteractions, and current diagnostic approaches, along with major management strategies, includingcultural practices, host resistance, biological control, botanical extracts, chemical control, diseaseforecasting, and integrated disease management. It also highlights the impacts of climate changeon disease distribution and severity, as well as recent advances in molecular breeding, genomeediting, and precision agriculture. Overall, sustainable management of potato late blight requiresintegrating resistant cultivars, environmentally friendly control measures, disease forecasting, andjudicious fungicide use. Continued research on durable resistance, climate-smart management, andemerging biotechnological tools will be essential to enhance potato resilience and ensure futurefood security.","由致病疫霉（Phytophthora infestans）引起的马铃薯晚疫病仍是影响全球马铃薯生产的最具破坏性的病害之一，造成严重的产量和经济损失。本文综述了该病原菌的生物学特性、病害循环、流行病学、寄主—病原互作及当前诊断方法，并总结了主要防控策略，包括栽培措施、寄主抗性、生物防治、植物提取物、化学防治、病害预测及病害综合管理。文章还重点讨论了气候变化对病害分布和严重度的影响，以及分子育种、基因组编辑和精准农业方面的最新进展。总体而言，马铃薯晚疫病的可持续治理需要整合抗病品种、环境友好型防控措施、病害预测和合理使用杀菌剂。持续开展持久抗性、气候智慧型管理及新兴生物技术工具的研究，对于增强马铃薯抗逆性和保障未来粮食安全至关重要。","Potato Journal","2026-10-15T00:00:00Z",82,{"impact":194,"substance":210,"depth":18,"authority":91,"freshness":20,"relevant":21,"comment":298},"核心期刊综述，系统梳理晚疫病生物学、气候变化影响与可持续防控，对马铃薯病害防控与智慧植保具参考价值，但属综述类论文，非突破性成果。",[300],{"name":294,"url":291},[26,29,302,303,304],"分子育种","气候变化","晚疫病",{"code":32,"slug":33,"name":34,"path":35,"parent_code":36},[307],{"code":308,"slug":309,"name":310,"path":311,"parent_code":312},"H7","climate","气候适应与防灾减灾","\u002Ftopic\u002Fenvironment\u002Fclimate","H",{"status":45,"locked":13,"version":46,"method":47,"evidence":314},{"candidates":315,"agricultural_evidence":51},[316,321,326,332,339,344,350],{"code":32,"score":134,"supported":51,"title":317,"abstract":319,"tags":320},[318],"potato",[26,318],[26],{"code":308,"score":135,"supported":51,"title":322,"abstract":324,"tags":325},[323],"climate change",[303],[303],{"code":327,"score":254,"supported":51,"title":328,"abstract":329,"tags":331},"F2",[],[302,330],"molecular breeding",[302],{"code":333,"score":79,"supported":51,"title":334,"abstract":335,"tags":338},"I1",[],[336,337],"精准农业","precision agriculture",[],{"code":39,"score":223,"supported":51,"title":340,"abstract":341,"tags":343},[],[342],"生物防治",[29],{"code":345,"score":62,"supported":51,"title":346,"abstract":347,"tags":349},"A8",[],[348],"粮食安全",[],{"code":68,"score":21,"supported":13,"title":351,"abstract":352,"tags":353},[],[],[29],[355,356],"马铃薯 晚疫病 致病疫霉","Potato Journal 晚疫病","马铃薯晚疫病致病疫霉-5158",0,"10.56093\u002Fpotatoj.v53i1.181670",{"doi":359,"openalex_id":361,"authors":362,"venue":294,"cited_by_count":358,"oa_url":291,"card":365,"direction":371,"ingested_from":372},"W7222725701",[363],{"name":364,"orcid":8},"Sujata Bashyal",{"tldr":366,"method":367,"finding":368,"direction":369,"opportunity":370},"综述马铃薯晚疫病的生物学、流行学、气候变化影响及可持续防控策略。","文献综述，整合病原生物学、诊断、抗性育种、生物防治与精准农业技术。","可持续防控需整合抗病品种、绿色措施、病害预测与合理用药。","农业人工智能与决策模型","可结合气象与遥感数据构建气候智慧型晚疫病预测模型，支撑精准施药决策。","智慧农业 \u002F 农业物联网","openalex","2026-10-17T23:30:12.547775Z"]