[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"topic-IAA":3},{"name":4,"kind":5,"tokens":6,"total":7,"page":7,"page_size":8,"items":9},"IAA","tag",[4],1,100,[10],{"id":11,"title":12,"url":13,"summary":14,"summary_zh":15,"content":16,"source_name":17,"source_url":15,"published_at":18,"category":19,"cover_url":15,"hotness":20,"is_selected":21,"score":22,"score_detail":23,"sources":30,"tags":32,"primary_topic":38,"secondary_topics":44,"classification":51,"search_phrases":76,"slug":79,"view_count":80,"doi":15,"paper":15,"created_at":81},958,"江苏农科院植保所：水稻二化螟ROS响应纳米农药创制方面取得重要进展","https:\u002F\u002Fwww.jaas.ac.cn\u002Fxww\u002Fxsky\u002Fart\u002F2026\u002Fart_31b1c89c42cd452bb905e1d1e84d3a12.html","江苏省农科院植保所农药应用创新团队在水稻二化螟防治上取得重要进展，基于ROS响应性金属-多酚网络智能递送农药，开发出一种安全、高效、生态兼容的多功能新型纳米农药。该纳米制剂对非靶标生物(斑马鱼、鼠成纤维细胞、人脐静脉内皮细胞)表现出低急性毒性，有效维持土壤微生物群落的生态稳定与功能多样性；伴随着铁元素和单宁酸的释放及植物体内生长素(IAA)信号途径的协同激活，显著促进水稻根系的生长发育，实现「防虫」与「促生」的双重功效。论文发表于Journal of Nanobiotechnology，研究得到长三角科技创新共同体联合攻关(2025CSJZN01300)和国家水稻产业技术体系(CARS-01)等项目资助。",null,"近日，植保所农药应用创新团队在《Journal of Nanobiotechnology》（中科院1区TOP期刊，IF5year=12.3）上发表了题为“Reactive Oxygen Species (ROS)-Responsive Deliveryof Chlorantraniliprole by a Nanoscale Metal-Phenolic Network for SystemicControl of Rice Striped Stem Borer”的研究成果。该工作成功研发了一种基于响应活性氧（ROS）的金属-多酚网络纳米农药递送系统，实现了杀虫剂的精准系统释放，并显著促进水稻根系生长，有效控制二化螟（Chilo suppressalis）的危害。\n\n二化螟是水稻生态系统中危害突出的鳞翅目钻蛀性害虫，对水稻安全生产与粮食安全构成严重威胁。受田间耕作制度变革等因素影响，近年来该虫田间发生程度持续加重。由于二化螟幼虫潜藏于水稻茎秆内部蛀食为害，隐蔽性极强，常规叶面喷雾施药难以抵达害虫取食靶位，药剂有效利用率偏低。氯虫苯甲酰胺悬浮剂长期大剂量粗放施用已诱发二化螟种群产生高水平抗药性，显著制约了该药剂在二化螟绿色精准防控中的应用效能。团队利用单宁酸-铁络合物等材料，成功构建了基于金属-多酚网络的氯虫苯甲酰胺（CAP）纳米递送系统（CAP@TF-PEG）。该载体能够响应害虫取食诱导植物产生的活性氧（ROS）信号，实现包裹农药在受损部位的靶向智能释放，显著增强了其在植株内韧皮部介导的系统传导性能，大幅提高了田间防效和杀虫持效期。其次，通过转录组学（RNA-seq）分析发现，CAP@TF-PEG递送策略不仅维持了CAP的杀虫机制，还进一步强化了其对害虫表皮合成的抑制作用，并显著下调了脂质代谢、跨膜转运及解毒相关的基因，从代谢和分子层面协同破坏了害虫的生理稳态。最后，该纳米制剂展现出了优异的环境与生态兼容性。它不仅对非靶标生物（如斑马鱼、鼠成纤维细胞和人脐静脉内皮细胞）表现出低急性毒性，且有效维持了土壤微生物群落的生态稳定与功能多样性。尤为重要的是，伴随着铁元素和单宁酸的释放，以及植物体内生长素（IAA）信号途径的协同激活，该制剂能显著促进水稻根系的生长发育，实现了“防虫”与“促生”的双重功效。\n\n综上所述，本研究全面展示了基于ROS响应性金属-多酚网络智能递送农药的巨大优势，结合靶向控害与植物生长促进作用，开发了一种安全、高效、生态兼容的多功能新型纳米农药，为新一代以植物健康为导向的农药递送系统的设计提供了重要参考。徐德进副研究员为本文的第一作者，博士研究生周正浩和乔恒为论文并列第一作者，团队负责人谭永安博士（末位通讯）和南京大学洪浩教授为论文共同通讯作者，江苏省农业科学院为第一完成单位。上述研究工作得到了长三角科技创新共同体联合攻关（2025CSJZN01300）和国家水稻产业技术体系（CARS-01）等项目的资助。","江苏省农业科学院 2026-08-19","2026-08-19T00:00:00Z","报道",10,false,85,{"impact":24,"substance":25,"depth":26,"authority":27,"freshness":28,"relevant":7,"comment":29},25,24,19,14,3,"纳米农药智能递送系统研究，兼具防虫促生双重功效，发表于中科院1区TOP期刊，科研价值高，但发布已超一周，时效性偏低。",[31],{"name":17,"url":13},[33,34,35,36,37,4],"植保所","二化螟","江苏省农科院","ROS响应","纳米农药",{"code":39,"slug":40,"name":41,"path":42,"parent_code":43},"A1","rice","水稻","\u002Ftopic\u002Ffield-crops\u002Frice","A",[45],{"code":46,"slug":47,"name":48,"path":49,"parent_code":50},"F4","crop-protection","农药与绿色防控","\u002Ftopic\u002Finputs-equipment\u002Fcrop-protection","F",{"status":52,"locked":21,"version":53,"method":54,"evidence":55},"classified","2026-10-22.2","rules",{"candidates":56,"agricultural_evidence":59},[57,65,70],{"code":46,"score":58,"supported":59,"title":60,"abstract":63,"tags":64},23,true,[61,62],"农药","植保",[61,62],[37],{"code":39,"score":66,"supported":59,"title":67,"abstract":68,"tags":69},11,[41],[41],[],{"code":71,"score":28,"supported":59,"title":72,"abstract":73,"tags":75},"H2",[],[74],"土壤",[],[77,78],"江苏省农科院 纳米农药 二化螟 植保所","江苏省农科院 纳米农药","江苏省农科院纳米农药二化螟植保所-958",2,"2026-08-26T00:09:31.050061Z"]