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Journal）》上。\n\n杂草防控是紫花苜蓿生产中的关键环节，直接影响饲草产量品质与生产效益。然而，长期单一施用除草剂会引发杂草抗药性上升、土壤残留等问题，制约紫花苜蓿绿色可持续规模化种植。\n\n研究团队构建了适配紫花苜蓿的高效引导编辑系统，并进一步对三个抗除草剂靶标基因同时定点突变，创制出了兼具烟嘧磺隆高抗性与高效氟吡甲禾灵耐受性的紫花苜蓿新种质。该研究首次在紫花苜蓿中实现了多基因引导编辑，为紫花苜蓿生物育种与多抗种质创新提供了新型技术工具和优异种质资源。\n\n该研究得到国家自然科学基金、中国农业科学院科技创新工程等项目支持。（通讯员：崔艳）\n\n原文链接：https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fpbi.70752\n\n![Image 8: image.png](https:\u002F\u002Fcaas.cn\u002Fimages\u002F2026-09\u002Fff58b03ac069469f9b2a4c67041dac21.png)\n\n打印本页\n\n关闭本页\n\n[院网信息发布与管理](https:\u002F\u002Fcaas.cn\u002Fywxxfbygl\u002Findex.htm)[最新动态](https:\u002F\u002Fcaas.cn\u002Fywxxfbygl\u002Findex.htm)\n\n*   [科技赋能沃野 夯实中原粮仓 专家下沉一线护航玉米丰产丰收](https:\u002F\u002Fcaas.cn\u002Fxwzx\u002Fhzdznew\u002F21942b3ab22c47fc935218df967152b7.htm)2026-09-28  \n*   [秋收图景](https:\u002F\u002Fwww.caas.cn\u002Fzt\u002F2026qstj\u002Findex.htm)2026-09-28  \n*   [ARC生物耦合技术赋能兰考花生产业增产增效](https:\u002F\u002Fcaas.cn\u002Fxwzx\u002Fkyhd\u002Ffc42a7cb57414940a787e12f23de332e.htm)2026-09-28  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京公网安备11010802048565号](http:\u002F\u002Fwww.beian.gov.cn\u002Fportal\u002FregisterSystemInfo?recordcode=11010802048565)","中国农业科学院网·2026年10月","2026-10-02T00:00:00Z","报道",false,85,{"impact":584,"substance":321,"depth":585,"authority":586,"freshness":173,"relevant":455,"comment":587},24,16,15,"国家级科研机构首次在苜蓿中实现多基因引导编辑，属生物育种领域实质性突破，具备进入每日精选的价值。",[589,590,593],{"name":578,"url":575},{"name":591,"url":592},"中国科学报·2026年10月4日","https:\u002F\u002Fwap.sciencenet.cn\u002Fmobile.php?cat=T&id=572493&mobile=1&type=detail",{"name":594,"url":595},"中国科学报 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紫花苜蓿","苜蓿 引导编辑 耐除草剂","中国农科院生物所紫花苜蓿-4125","2026-10-04T00:09:06.421141Z",{"id":641,"title":642,"url":643,"summary":644,"summary_zh":11,"content":11,"source_name":645,"source_url":11,"published_at":646,"category":580,"cover_url":11,"hotness":385,"is_selected":581,"score":647,"score_detail":648,"sources":652,"tags":654,"primary_topic":659,"secondary_topics":660,"classification":661,"search_phrases":677,"slug":680,"view_count":400,"doi":11,"paper":11,"created_at":681},3955,"湖北省农科院发布2026年9-11月政府采购意向——华中微生物农药综合评价中心建设项目","https:\u002F\u002Fwww.ccgp-hubei.gov.cn\u002Fnotice\u002F202609\u002Fcgyxgg_8a84806fa0aec2bf01a0f17c23b0136b.html","湖北省农业科学院公开2026年9月至11月政府采购意向，华中微生物农药综合评价中心建设项目预算金额合计超580万元，采购高通量基因测序系统等仪器设备。建设内容包括建成微生物农药评价研究子平台3个以上；构建国内登记微生物农药生产菌种（毒种）活体库、基因库及数据库1个，入库菌种>50株；建立新型微生物农药的分析检测方法2-3项、田间精准应用技术不少于3项；构建微生物农药综合评价智能管理系统1套。","湖北省政府采购网·2026年09月","2026-09-25T08:00:00Z",75,{"impact":361,"substance":321,"depth":585,"authority":649,"freshness":650,"relevant":455,"comment":651},13,6,"省级农科院重大科研平台采购意向，含预算、菌种库与检测方法等具体指标，信息增量足，但属省级细分领域进展，时效略滞后。",[653],{"name":645,"url":643},[598,655,656,657,658],"微生物农药","政府采购","农业科技平台","农业数据库",{"code":104,"slug":105,"name":106,"path":107,"parent_code":72},[],{"status":607,"locked":581,"version":4,"method":608,"evidence":662},{"candidates":663,"agricultural_evidence":612},[664,669,673],{"code":104,"score":416,"supported":612,"title":665,"abstract":667,"tags":668},[666],"农药",[666],[655],{"code":88,"score":455,"supported":581,"title":670,"abstract":671,"tags":672},[],[],[598],{"code":542,"score":455,"supported":581,"title":674,"abstract":675,"tags":676},[],[],[656],[678,679],"湖北省农科院 微生物农药 综合评价中心","微生物农药 高通量基因测序","湖北省农科院微生物农药综合评价中心-3955","2026-10-02T11:53:12.858340Z",{"id":683,"title":684,"url":685,"summary":686,"summary_zh":11,"content":687,"source_name":688,"source_url":11,"published_at":689,"category":580,"cover_url":11,"hotness":385,"is_selected":581,"score":582,"score_detail":690,"sources":692,"tags":694,"primary_topic":697,"secondary_topics":698,"classification":701,"search_phrases":727,"slug":730,"view_count":69,"doi":11,"paper":11,"created_at":731},2452,"中国农科院生物所开发引导编辑系统创制耐双除草剂紫花苜蓿新种质(Plant Biotechnology Journal)","https:\u002F\u002Fbri.caas.cn\u002Fxwdt\u002Fkyjz\u002F15de4625557e461484535a717789a7a9.htm","中国农科院生物所饲草作物功能基因组创新团队开发了紫花苜蓿高效引导编辑技术体系,并创制了耐双除草剂紫花苜蓿新种质,为饲草绿色轻简化栽培和分子育种提供了重要技术工具与种质资源。研究团队通过优化驱动引导编辑核心元件的启动子,构建适用于紫花苜蓿的引导编辑系统,进一步对 MsALS1、MsALS2 及 MsACC1 基因同时定点突变,创制出兼具烟嘧磺隆高抗性与高效氟吡甲禾灵耐受性的紫花苜蓿新种质。该研究首次在紫花苜蓿中实现多基因引导编辑。成果发表在《Plant Biotechnology Journal》。","### 生物所开发引导编辑系统并创制耐双除草剂紫花苜蓿新种质\n\n近日，中国农业科学院生物技术研究所饲草作物功能基因组创新团队开发了紫花苜蓿高效引导编辑技术体系，并创制了耐双除草剂紫花苜蓿新种质，为饲草绿色轻简化栽培和分子育种提供了重要技术工具与种质资源。相关研究成果发表在《植物生物技术杂志（Plant Biotechnology Journal）》上。\n\n![Image 1](https:\u002F\u002Fbri.caas.cn\u002Fimages\u002F2026-09\u002F3b6cc618b82e41f0935363d23fe6c309.png)\n\n杂草防控是紫花苜蓿生产中的关键环节。长期单一施用除草剂易诱导杂草产生抗药性，同时带来土壤残留风险。创制新型多抗除草剂紫花苜蓿种质，对提升饲草产量与品质、降低田间管理成本、推进产业绿色可持续发展具有重要意义与应用前景。\n\n研究团队通过优化驱动引导编辑核心元件的启动子，构建了适用于紫花苜蓿的引导编辑系统。进一步对MsALS1、MsALS2及MsACC1基因同时定点突变，创制出了兼具烟嘧磺隆高抗性与高效氟吡甲禾灵耐受性的紫花苜蓿新种质。该研究首次在紫花苜蓿中实现了多基因引导编辑，为紫花苜蓿生物育种与多抗种质创新提供了新型技术工具和优异种质资源。\n\n生物所博士研究生李世豪为论文第一作者。牛丽芳研究员、林浩研究员为共同通讯作者。中国农业大学宗媛教授分享了pB-CMPE-ePPEplus载体、广州大学关跃峰教授分享了pGES401载体。该研究工作得到了国家自然科学基金(32325035)和中国农业科学院科技创新工程等项目的支持。\n\n原文链接：https:\u002F\u002Fonlinelibrary.wiley.com\u002Fdoi\u002F10.1111\u002Fpbi.70752","中国农科院生物所 2026-09-13","2026-09-12T16:00:00Z",{"impact":321,"substance":321,"depth":361,"authority":586,"freshness":173,"relevant":455,"comment":691},"国家级科研机构在紫花苜蓿上首次实现多基因引导编辑并创制耐双除草剂新种质，方法新颖、结论可靠，对饲草绿色轻简化栽培有实质推动，值得进入每日精选。",[693],{"name":688,"url":685},[598,695,599,696,600],"种质创新","饲草产业",{"code":364,"slug":365,"name":366,"path":367,"parent_code":332},[699,700],{"code":256,"slug":257,"name":258,"path":259,"parent_code":200},{"code":104,"slug":105,"name":106,"path":107,"parent_code":72},{"status":607,"locked":581,"version":4,"method":608,"evidence":702},{"candidates":703,"agricultural_evidence":612},[704,708,712,716,721],{"code":364,"score":585,"supported":612,"title":705,"abstract":706,"tags":707},[614],[616,614],[600,696],{"code":256,"score":649,"supported":612,"title":709,"abstract":710,"tags":711},[614],[614],[600,696],{"code":104,"score":524,"supported":612,"title":713,"abstract":714,"tags":715},[624],[624],[],{"code":88,"score":408,"supported":612,"title":717,"abstract":718,"tags":720},[],[719],"分子育种",[599,598],{"code":80,"score":722,"supported":612,"title":723,"abstract":724,"tags":726},3,[],[725],"种质资源",[],[728,729],"基因编辑 生物育种 种质创新 紫花苜蓿","基因编辑 生物育种","基因编辑生物育种种质创新紫花苜蓿-2452","2026-09-15T00:04:21.833636Z",{"id":733,"title":734,"url":735,"summary":736,"summary_zh":11,"content":737,"source_name":738,"source_url":11,"published_at":739,"category":580,"cover_url":11,"hotness":385,"is_selected":581,"score":740,"score_detail":741,"sources":743,"tags":745,"primary_topic":749,"secondary_topics":750,"classification":751,"search_phrases":768,"slug":771,"view_count":650,"doi":11,"paper":11,"created_at":772},1853,"AI驱动高效挖掘杀虫蛋白——植保所利用人工智能技术挖掘并验证新型杀虫蛋白","https:\u002F\u002Fnews.sciencenet.cn\u002Fhtmlnews\u002F2026\u002F9\u002F570902.shtm","中国农业科学院植物保护研究所抗虫功能基因研究与利用创新团队利用人工智能技术根据蛋白质结构特征，挖掘了一批不同生物来源的候选杀虫蛋白，并验证其杀虫活性；同时构建了高效杀虫蛋白生产平台。相关研究成果发表在《生物技术趋势》(Trends in Biotechnology)上。","[![Image 1: 科学网新闻频道](https:\u002F\u002Fnews.sciencenet.cn\u002Fimages\u002Fnews.jpg)](https:\u002F\u002Fnews.sciencenet.cn\u002F)\n\n[生命科学](https:\u002F\u002Fwww.sciencenet.cn\u002Flife\u002F) | 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[论文](https:\u002F\u002Fpaper.sciencenet.cn\u002F) | [绘图](https:\u002F\u002Fvisual-web.sciencenet.cn\u002F) | [视频·直播](https:\u002F\u002Fblog.sciencenet.cn\u002Fblog.php?mod=video) | [小柯机器人](https:\u002F\u002Fpaper.sciencenet.cn\u002FAInews) | [医学科普](https:\u002F\u002Fyxkp.sciencenet.cn\u002F)\n\n作者：李晨,郭建英 来源：中国科学报 发布时间：2026\u002F9\u002F5 0:35:06 选择字号：小 中 大 AI驱动高效挖掘杀虫蛋白 近日，中国农业科学院植物保护研究所抗虫功能基因研究与利用创新团队 利用人工智能技术，挖掘了一批不同生物来源的候选杀虫蛋白，并验证了其杀虫活性。相关研究成果发表在《生物技术趋势》（_**Trends in Biotechnology**_）上。 苏云金芽胞杆菌产生的杀虫蛋白因高效、环保等特点被广泛应用，但现有资源主要来源于少数传统微生物，迫切需要更多来源广泛、功能新颖的杀虫蛋白。 研究团队突破传统依赖微生物资源筛选的方式，利用人工智能技术，根据蛋白质结构特征，挖掘了一批不同生物来源的候选杀虫蛋白，并验证了其杀虫活性。 研究团队还构建了高效杀虫蛋白生产平台，可帮助微生物快速表达和验证新发现的杀虫蛋白，加快功能评价和应用开发。该研究建立了从人工智能辅助发现、功能验证到应用开发的技术路径，为抗虫作物育种和新型绿色生物农药创制提供了新的基因资源和技术支撑。 该研究得到国家重点研发计划、中国农业科学院科技创新工程、国家自然科学基金等项目资助。 相关论文信息：https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.tibtech.2026.07.023 版权声明：凡本网注明“来源：中国科学报、科学网、科学新闻杂志”的所有作品，网站转载，请在正文上方注明来源和作者，且不得对内容作实质性改动；微信公众号、头条号等新媒体平台，转载请联系授权。邮箱：shouquan@stimes.cn。\n\n打印 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2026-09-05","2026-09-05T00:00:00Z",77,{"impact":321,"substance":508,"depth":585,"authority":649,"freshness":650,"relevant":455,"comment":742},"AI挖掘新型杀虫蛋白，为抗虫育种和绿色农药提供新资源，具行业突破意义。",[744],{"name":738,"url":735},[746,598,747,748],"农业人工智能","杀虫蛋白","绿色农药",{"code":104,"slug":105,"name":106,"path":107,"parent_code":72},[],{"status":607,"locked":581,"version":4,"method":608,"evidence":752},{"candidates":753,"agricultural_evidence":612},[754,760,764],{"code":104,"score":755,"supported":612,"title":756,"abstract":758,"tags":759},9,[757],"植保",[],[748],{"code":88,"score":455,"supported":581,"title":761,"abstract":762,"tags":763},[],[],[598],{"code":24,"score":455,"supported":581,"title":765,"abstract":766,"tags":767},[],[],[746],[769,770],"农业人工智能 杀虫蛋白 生物育种 绿色农药","农业人工智能 杀虫蛋白","农业人工智能杀虫蛋白生物育种绿色农药-1853","2026-09-08T00:07:13.062604Z",{"id":774,"title":775,"url":776,"summary":777,"summary_zh":11,"content":11,"source_name":778,"source_url":11,"published_at":779,"category":580,"cover_url":11,"hotness":385,"is_selected":612,"score":101,"score_detail":780,"sources":782,"tags":784,"primary_topic":786,"secondary_topics":787,"classification":788,"search_phrases":803,"slug":806,"view_count":650,"doi":11,"paper":11,"created_at":807},1557,"中国农业科学院植保所：AI 驱动高效挖掘杀虫蛋白——Trends in Biotechnology 在线发表","https:\u002F\u002Fwww.caas.cn\u002Fxwzx\u002Fkyhd\u002Fca6ff732fa994da9aba93f296ff1df6c.htm","近日，中国农业科学院植物保护研究所抗虫功能基因研究与利用创新团队在新型杀虫蛋白发现与利用方面取得重要进展。研究团队突破传统依赖微生物资源筛选的方式，利用人工智能技术根据蛋白质结构特征挖掘了一批不同生物来源的候选杀虫蛋白，并验证其杀虫活性；研究团队还构建了高效杀虫蛋白生产平台，可帮助微生物快速表达和验证新发现的杀虫蛋白，加快功能评价和应用开发。该研究建立了从 AI 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